Eric Dane, 'Euphoria' Actor, Dies at 53 After ALS Diagnosis

Eric Dane dies at 53

Actor Eric Dane died on Thursday at the age of 53. A representative for the actor confirmed to The Hollywood Reporter that his death followed a diagnosis of ALS, or amyotrophic lateral sclerosis.

Co-stars and colleagues pay tribute

News of his passing prompted an immediate outpouring of tributes from former co-stars and colleagues. They remembered him as a gifted performer with a sharp sense of humor.

Selma Blair, who starred with Dane in the WB series Zoe, Duncan, Jack & Jane, shared a clip of them together on her Instagram Story. "I love you. And yours," she wrote.

A career spanning television and film

Dane was best known for his role as Dr. Mark "McSteamy" Sloan on ABC's long-running medical drama Grey's Anatomy. He appeared on the show from 2006 to 2012, becoming a fan-favorite character.

His other notable television roles included:

• Jason Dean on Charmed
• Cal Jacobs on HBO's Euphoria
• Lead roles in series like The Last Ship and Grey's Anatomy spinoff Private Practice

In film, Dane recently appeared alongside Will Smith and Martin Lawrence in Bad Boys: Ride or Die. His career also included roles in movies like Marley & Me and Valentine's Day.

Remembered for his professionalism and warmth

Co-stars emphasized his positive presence on set. Many shared personal anecdotes about his kindness and collaborative spirit.

Dane is survived by his wife, actress Rebecca Gayheart, and their two children. The family has requested privacy during this time.