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New mucosal vaccine clears C. diff from gut in animal models
A mucosal vaccine clears C. difficile from the gut, preventing infection and recurrence, unlike traditional systemic vaccines.
887 articles
A mucosal vaccine clears C. difficile from the gut, preventing infection and recurrence, unlike traditional systemic vaccines.
DeepRare is an AI system using large language models to diagnose rare diseases. It analyzes patient data to suggest ranked diagnoses with evidence, outperforming existing methods and showing high accuracy in global tests.
A study found that X's algorithm shifts users' political views toward conservatism by promoting conservative content and demoting traditional media. Switching to the algorithmic feed increased engagement and conservative opinions, but switching back had no effect. The algorithm's influence persists by changing who users follow.
HIV-1 integrase forms an octamer filament with RNA inside the viral core, binding to the capsid lattice. This interaction is crucial for packaging viral RNA, and disrupting it leads to defective viruses.
New study finds Heimdallarchaeia, the closest archaeal relatives to eukaryotes, are widespread in marine sediments and had aerobic metabolism, suggesting the Asgard-eukaryotic ancestor could produce hydrogen and use oxygen.
Social conditions shape male parenting in mice, with isolation increasing care and group living boosting infanticide. This variation is linked to activity in a brain region where the Agouti gene reduces care, showing context, not ability, drives paternal behavior.
Scientists found "proto-point" centromeres in yeast, showing how compact, genetic centromeres evolved from ancestral, repeat-rich ones. They originated from retrotransposons, linking selfish DNA to essential chromosome function.
Bacteria's Clover anti-phage system uses enzymes to dynamically control a defense enzyme, balancing viral restriction with avoiding cellular toxicity.
LLMs need moral competence, not just performance, for real-world roles. Challenges include fake reasoning, complex moral factors, and global standards. A roadmap with new evaluations is proposed.
Cytology helps detect cancer early but is subjective. A new AI system automates the process, achieving high accuracy in cervical cancer screening and enabling objective, scalable diagnostics.
New photonics system enables 512 Gbps fiber and 400 Gbps wireless using same hardware, supporting ultra-dense, high-speed networks.
New glass-based optical storage uses lasers to write data, achieving high density and durability for long-term archival, with potential data lifetimes over 10,000 years.